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doi: 10.1016/s0091-3057(97)90017-4

[DOI] [PubMed] [Google Scholar] 118.Zinman B, Gerich J, Buse JB, Lewin A, Schwartz S, Raskin P, Hale PM, Zdravkovic M, Blonde L LEAD-4 Study Investigators

Widely prescribed and wildly popular, particularly for the unprecedented weight loss they confer, theyve shown promise in myriad organ systems

In a late-stage trial, participants lost an average of 11.2% of their body weight

37: 187-204.e7

As patients compare experiences, some report surprisingly meaningful symptom relief less bloating, fewer flares, even improved painwhile others notice no change or develop worsening gastrointestinal discomfort
