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Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro

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The second strategy focuses on DPP-4 inhibitors, which prevent the rapid degradation of endogenous GLP-1 by inhibiting the DPP-4 enzyme, thereby extending the hormone's activity