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Moreover, compensation for the loss of GLP-2R action, including by GLP-1R signaling, maintained expansion of intestinal length, weight, and preserved body weight gain in response to chronic cold stress
After applying all eligibility criteria, 83,193 patients from 57 healthcare organizations were eligible, comprising 33,197 in the dual therapy group and 49,996 in the SGLT-2 inhibitor only group
Moreover, GLP-1 production has been shown in some neurons of the nucleus of the solitary tract (NTS) in the brain stem [for a review, see Holst (2007)]
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Furthermore, the timing of the obstruction, which correlated with the initiation of GLP-1 RA therapy, suggests a causal relationship
1993;264:R116R122
