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This makes it a triple agonist medication, the first of its kind

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By targeting glucagon receptors, Retatrutide directly increases energy expenditure and thermogenesis, promoting faster calorie burning and fat loss

GLP-1 receptor agonists improve MASH mostly via extrahepatic actions: 1 CNS appetite control weight loss systemic inflammation 2 Chylomicron synthesis & improve lipid metabolism 3 Bind gut immune cells anti-inflammatory + microbiome benefits 4 Reduce adipose & pancreatic inflammation

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