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FPG levels decreased in both the sitagliptin and saxagliptin arms (by 16.2 mg/dL and 10.8 mg/dL, respectively)

Clin Pharmacokinet 60:13351348 McGuire DK, Busui RP, Deanfield J et al (2023) Effects of oral semaglutide on cardiovascular outcomes in individuals with type 2 diabetes and established atherosclerotic cardiovascular disease and/or chronic kidney disease: design and baseline characteristics of SOUL, a randomized trial

The difference between vial and pen storage primarily relates to air exposure: vials with unused doses can be re-capped and re-refrigerated between uses, while pens are single-use devices that must be discarded once opened, even if medication remains

In its Departmental Plan, Health Canada commits to proposing regulatory amendments to enable more innovation in drug clinical trials and make Canada a more attractive place for companies to invest. It also plans to introduce amendments aimed at improving predictability for regulated parties and streamlining authorisation processes for health products, while maintaining safety, effectiveness and quality standards.

Reach: 60 - 100 Million people (The Affluent India cohort)

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