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Genetic Predispositions in GLP-1 Pathways: How Personalization Supports Canadian Treatment Selection Emerging evidence suggests that genetic variants in GLP-1 receptor (GLP1R rs6923761) and glucose-dependent insulinotropic polypeptide receptor (GIPR rs1800437) pathways may influence individual responses to GLP-1 therapy

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These processes interact with one another in a pathological feed-forward cycle, ultimately yielding functional and structural kidney abnormalities characteristic of diabetic kidney disease (DKD) (Fig

In Study B, the average age was 39 years

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