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They evaluated voluntary alcohol consumption using the drinking-in-the-dark (DID), alcohol deprivation effect (ADE), and intermittent access two-bottle choice (IA2BC) paradigms

GHSR is a member of the seven transmembrane G protein-coupled receptor family, and is expressed in multiple brain regions, including the hypothalamus and pituitary [3], as well as in several pancreatic cell types (, , and acinar cells) [4, 5], throughout the gastrointestinal tract (stomach, intestine and vagal afferent neurons) [6], and in the adipose tissue [7]

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This temporary gastrointestinal response happens because GLP-1 agonists slow stomach emptying and increase feelings of fullnessthe same mechanisms that support weight loss