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Researchers at UC Irvine issue a warning that GLP-1RAs may be dangerous for children Source: UC Irvine School of Medicine Irvine, CA, August 28, 2023 A team of clinicians, exercise scientists, pharmaceutical scholars, ethicists and behavioral experts at the University of California, Irvine, outlined their concerns that the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) to treat childhood obesity and type 2 diabetes may have unintended and adverse consequences for childrens health

According to Novo Nordisk, the maker of Saxenda and Wegovy, they recommend eating bland, low-fat foods, such as crackers, toast and rice

However, truncated GLP-1 was clearly insulinotropic at much lower (picomolar) concentrations compared to the extended GLP-1 sequence [1,2]

Real-world data confirms these results persist when patients maintain medication use and lifestyle modifications

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It is also important that the pill be swallowed whole