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Description
Dose reduction or temporary treatment interruption, followed by slower re-titration, often allows continued therapy with improved tolerance

- The medial upper third of the tight (about 5 cm below the inguinal crease)

A patient requesting cosmetic abdominal fat reduction at a BMI that appears modest by Western criteria may already carry significant cardiometabolic risk

The patient loses weight, including lean mass

Orskov C, Poulsen SS, Mller M, Holst JJ

Orexin-A and leptin change inversely in fasting non-obese subjects