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Description
Treatment duration was estimated using prescription span, and adherence could not be confirmed

As shown in Scheme 26
The most effective approach layers multiple interventions simultaneously

These agents further optimize glucose utilization by activating glycolytic enzymes such as hexokinase and phosphofructokinase, thereby enhancing glycolytic flux (90)

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There's no evidence saying these drugs cause C cell hyperplasia in humans, so the FDA gave it a black box warning until we know more
