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doi: 10.1007/s00404-015-3976-7

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[1] [2] As of 20242025, retatrutide remains under clinical investigation and has not been approved by the Medicines and Healthcare products Regulatory Agency (MHRA) in the United Kingdom, nor by the European Medicines Agency (EMA) or the US Food and Drug Administration (FDA) for routine clinical use

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Darren McGuire, a professor in UT Southwesterns Department of Internal Medicine and member of the Division of Cardiology has been a part of ongoing research that shows the drugs reduce the risk of cardiovascular death, heart attack and stroke