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J Am Board Fam Med 26:203210 Meier JJ (2012) GLP-1 receptor agonists for individualized treatment of type 2 diabetes mellitus

doi: 10.1038/s41746-022-00628-3

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They can assess whether metformin is a good option for you based on your personal and family health history, any medications or supplements you take, and your overall health goals

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In humans, plasma DPP-4 activity is higher in patients with non-alcoholic fatty liver disease irrespective of their glucose tolerance, whereas it was not elevated in patients with T2DM in whom liver disease had been excluded (84)
