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Description
Rapid weight reduction triggers gallbladder contractions that may dislodge existing stones or promote new formation
Escalate to renal replacement therapy when indicated
Gut Microbes 17:2505269
A Review of the SUSTAIN Clinical Trial Programme
Typical interventions include smoking cessation, weight loss, management of diabetes mellitus, and adoption of loose cotton clothing
Topline results showed 28.7% average body weight loss at 68 weeks (26.6% placebo-adjusted, approximately 71.2 pounds) at the 12 mg dose peer-reviewed publication pending
