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When the right key is inserted, a series of activities is unlocked. In this case that key is GLP-1 and the unlocked activities are the release of insulin and the curbing of the production of glucagon

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This puts ASH1L at the heart of common networks of co-substrates, which are virtually linked across multiple neuropsychiatric disorders

Immunoblotting with anti-NEDD4, anti-FOXM1, and anti-YAP1 antibodies was performed on lysates derived from primary astrocytes exposed to varying H 2 O 2 concentrations for 1 h (A) or to 0.1 mM H 2 O 2 for different time intervals (D)

Stevens, Email: [email protected] Supplementary information Supplementary information is available for this paper at 10.1038/s41467-020-14934-5