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Dosages may be adjusted over time to improve tolerability and effectiveness

This systematic review evaluates the literature on the relationship between GLP-1 RA use and increased regurgitation and aspiration events to contextualize the existing, consensus-based guidelines put forth by the ASA in light of limited comparative evidence
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A: People with a personal or family history of MTC or MEN2 , prior pancreatitis , certain gallbladder or severe GI disorders, and those pregnant/breastfeeding should avoid or use only with specialist guidance

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