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A review of multiple studies concluded that individuals taking berberine reported a significant reduction in body weight and BMI

Nonetheless, limitations are noted

Results also showed that, while those taking 4 mg in the initial trial had lower levels of weight loss, this group also had a lower discontinuation rate due to adverse events when compared to those taking a placebo

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Patients may need to pay out of pocket, but the out of pocket cost is always disclosed upfrontthere are no surprises

The proportion of patients with comorbidities associated with fracture risk such as T2D (26.7%), cardiac disease (16.3%), and liver disease (11.2%) was also reported