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*** This was reported as a composite of death from cardiovascular causes and hospital admission for heart failure

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Collectively, these findings demonstrate sustained Exe4 expression and secretion by the liver following a single in vivo genome editing at the mouse Alb locus using LNP-mediated HITI, with no discernible side effects

[DOI] [PubMed] [Google Scholar] 469.Fernandez J., Valdeolmillos M

doi:10.1210/clinem/dgaa327 59

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