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1b,c), whereas control mice treated with either artificial cerebrospinal fluid or two different doses of IgG1 (a non-binding control antibody) maintained a stable body weight (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Telenga ED, Tideman SW, Kerstjens HAM, et al

Researchers have also observed promising improvements in metabolic markers and better preservation of lean muscle mass, says Burns

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While the findings of these studies still show the therapeutic relevance of PAS, it is unclear whether the same effects would be observed with more physiologically relevant concentrations
The numbers are specific: 4.9-5.3% across dose groups versus 0.9% placebo
