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Telehealth and patient satisfaction: a systematic review and narrative analysis

These include the impact of rapid weight loss on the body, potential hormonal shifts, and the possibility of medication-induced nutritional deficiencies

Regulators increasingly expect explicit acknowledgment of such uncertainty and clear plans to resolve it through biomarker-driven early-phase studies, rather than relying solely on associative epidemiology

Some investigational therapies even combine multiple hormones at once to strengthen appetite control, metabolism, and long-term weight management

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Data are currently distributed across many different systems, which can impede the conduct of collaborative and integrative research