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[35] conducted the first population-based study linked the UK CPRD with the Hospital Episodes Statistics database, examining the relationship between incretin-based medications and the incidence of hospitalization due to bile duct and gallbladder diseases

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N Engl J Med 2021

Effects of exenatide (exendin-4) on glycemic control over 30 weeks in patients with type 2 diabetes treated with metformin and a sulfonylurea

Further investigation is also needed in specific patient populations

Bilchik emphasizes, Careful consideration and ongoing investigation are essential to fully understand the impact of GLP-1 receptor agonists on colorectal cancer risk. By balancing the benefits and risks, healthcare providers can optimize treatment strategies and improve patient outcomes in the complex landscape of metabolic health and cancer prevention.