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namely, that had the company had its finger on the pulse of where nutrition and weight-loss were headed, it could have been at the forefront of this shift

The plasmid DNA encapsulated by LNPs demonstrated optimal characteristics for liver targeting, including particle size of approximately 100 nm, low polydispersity (approximately 0.2), neutral surface charges, and high DNA encapsulation efficiency (Supplementary Table 4) 25

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Manage gastrointestinal side effects, such as nausea or constipation, to ensure adherence and comfort

By week 812, this symptom typically disappears entirely without any intervention

Nat Rev Endocrinol (2026)