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L.ShamlooM.Mochly-RosenD

Impact of Selected Glucagon-like Peptide-1 Receptor Agonists on Serum Lipids, Adipose Tissue, and Muscle Metabolism-A Narrative Review

In a clinical study involving patients with type 2 diabetes, an almond-based diet with a low-carbohydrate content, which had been previously shown to possess marked prebiotic properties [110, 111], resulted in augmentation of the number of SCFA-producing bacteria species, such as Roseburia , Ruminococcus and Eubacterium , which led to an increase in fasting blood GLP-1 levels and also promoted antidepressive effects after three months [112]

Nevertheless, these findings prompted black box warnings on certain GLP-1 receptor agonists and have fueled ongoing post-marketing safety monitoring

Mounjaro: Mounjaro, on the other hand, takes a more comprehensive approach

Results Vim / mice fed an HFD showed less weight gain, less adiposity, improved glucose tolerance, and lower serum level of fasting glucose