glp-1 triple agonist Dual and Gut Peptide Agonists on the Horizon for the Treatment of Type 2 Diabetes and Obesity. An Overview of Preclinical and Clinical Data Calling retatrutide a “GLP-3” is

GLP-1 drugs may help with appetite and weight reduction, but they may also create clinically meaningful nutritional side effects, especially in patients with poor baseline diet quality, prolonged use, gastrointestinal side effects, or rapid weight loss

But it would be foolish not to consider them a valuable part of the arsenal.

Periyalwar, this side effect comes from the way GLP-1s affect the digestive tract

Prices were not found for any of these drugs in Austria or Belgium

In a study comprising 16 patients with T2DM and 12 non-diabetic controls, flow-mediated vasodilation was enhanced in both groups by GLP1 infusion of 0.4 pmol/kg/min, administered during a 2-hour hyperglycemic clamp [106]

doi:10.3389/fendo.2023.1085799 5