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Am I comfortable injecting myself with a pen or needle and syringe once a week or once a day

But understanding that Qsymia is not a GLP-1 is important when comparing costs, because you are comparing medications with different effectiveness levels
Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice

2022 Jan;10(1):9198

Semaglutide and Cardiovascular Outcomes in Obesity Without Diabetes

[DOI] [PMC free article] [PubMed] [Google Scholar] 41.Pharmacology, physiology, and mechanisms of incretin hormone action