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It recommended, instead, a combination of the glucose-regulating drug metformin, vitamin B12, the antidepressant bupropion, and naltrexone, a drug used to reduce cravings

Abstract Introduction The objective of the current study was to assess the long-term cost-effectiveness of once-weekly semaglutide 0.5 mg and 1.0 mg versus dulaglutide 1.5 mg for the treatment of patients with type 2 diabetes uncontrolled on metformin in the Chinese setting

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Finally, qualified libraries were sequenced on an Illumina NovaSeq platform (Illumina, San Diego, CA, USA) to generate 150 bp paired-end reads

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They emphasize that despite the availability of high-quality evidence and effective therapies, gaps in implementation remain substantial - particularly in underserved populations - and must be urgently addressed through better education, system-wide support, and policy alignment[82]