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For long peptides, such as GLP-1 analogs, deletion and isomeric impurities are generally the most prevalent at the crude stage

Constipation on semaglutide and constipation on tirzepatide respond well to fiber supplementation and increased water intake

This happens because the stomach muscles dont work properly and efficiently

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Other common adverse effects include injection site reactions, headache, and nasopharyngitis, but these effects do not usually result in discontinuation of the drug