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Saxenda (active ingredient: liraglutide) subcutaneous injection Initial FDA Approval: 2014 (liraglutide approved in 2010) Side Effect Update Date: May 28, 2025 Medication Description: For chronic weight management Updated Side Effects/Safety Information: A new warning section on Severe Gastrointestinal Adverse Reactions. An additional warning about the risk of serious kidney injury caused by dehydration due to gastrointestinal adverse effects like diarrhea and vomiting

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Also, Liraglutide was the world's first once-daily GLP-1RA drug

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One year after stopping the drug, patients had regained 60 % of the weight they had lost, representing 80 % of the total weight expected to return