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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Silveira SQ, et al

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Many patients need a combination approach

Expression of adenosine triphosphate (ATP)-sensitive potassium (K ATP ) channel subunits (sulphonylurea receptor 1 [SUR1] and inward-rectifier potassium channel 6.2 [Kir6.2]) has also been confirmed in K cells, and the addition of tolbutamide, a K ATP channel inhibitor, enhanced GIP release in primary mouse intestinal cultures [31]

Additionally, PGC-1 protein levels were measured
