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The commentary, Unintended Consequences of Glucagon-like Peptide-1 Receptor Agonists Medication in Children and Adolescents A Call to Action, was published as a perspective in the Journal of Clinical and Translational Science

Efficacy and safety of canagliflozin as add-on therapy to a glucagon-like peptide-1 receptor agonist in Japanese patients with type 2 diabetes mellitus: a 52-week, open-label, phase IV study

It is worth noting that many clinical trials of GLP-1 agonists excluded people with significant psychiatric illness, which may limit our understanding of effects in these populations

Strength training supports metabolism and mobility

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This is concerning because loss of skeletal muscle can lead to decreased strength, reduced functional capacity, and a lower resting metabolic rate, potentially making weight regain more likely after medication discontinuation