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So far, body weight management should be addressed as one of the leading therapeutic goals in T2D, with stringent targets must be achieved (71)

Hypothalamic alterations in neurodegenerative diseases and their relation to abnormal energy metabolism

In particular, the burden of CVD will intensify, given that people with diabetes experience a two- to fourfold increased risk of developing ASCVD compared to those without [6] and that CVD accounts for two-thirds of deaths in the overweight/obese population [7]
[DOI] [PubMed] [Google Scholar] 105.Indirect comparison of glucagon like peptide-1 receptor agonists regarding cardiovascular safety and mortality in patients with type 2 diabetes mellitus: network meta-analysis

Drucker, who began consulting with Novo Nordisk and other drug companies after his reptilian discovery, agrees that its a starting point for obesity: It will only scratch the surface of the problem in the population that needs to be healthier. But semaglutide is the most powerful obesity drug ever approved, he adds

Metaphors, such as referring to GLP-1 medications as training wheels for lifestyle changes, were also cited as helpful communication strategies
