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However, there was no association between GLP1RAs and reduced risk of postmenopausal breast cancer and no clear difference in breast cancer incidence among postmenopausal women treated with GLP1RAs compared to those treated with insulin or metformin [87]

Having pre-prepared, easy-to-eat, nutrient-dense foods on hand prevents the cycle of eating nothing (muscle loss, nutrient deficiency) or eating whatever is easiest (usually processed carbs)

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Collectively, these results demonstrated that the mTOR pathway has a role in lifespan extension in mammals, but raise the question as to why, with the exception of the study by Martin-Montalvo et al., metformin does not extend lifespan in mammals whereas rapamycin does (226)