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Recent guidance recommends individualized perioperative plans potentially holding doses before elective surgery
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Wang XH, Yang W, Holscher C, Wang ZJ, Cai HY, Li QS, et al
On May 7, 2019, PEX-168 was approved by China's CFDA for marketing
Large-scale clinical trials, including the SELECT cardiovascular outcome trial with over 17,000 participants, have not demonstrated increased overall cancer incidence with these medications compared to placebo groups
Fibrosis also improves with weight reduction, with 79.99 % or 10 % of weight reduction after 52 weeks of lifestyle intervention resulting in 50 % or 81 % of fibrosis regression, respectively, without any fibrosis worsening in adult patients with MASLD and baseline fibrosis on biopsy [39]
