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As these therapies become household names, the role of digital engagement grows more powerful

Dysfunctional adipose tissue promotes increased cardiovascular and diabetes disease risk via multiple pathways including increased free fatty acids (FFA) in the liver, infiltration of visceral fat deposits by proinflammatory macrophages resulting in chronic low-grade inflammation, and reduced buffering capacity for protective lipid storage [7]

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Other symptoms then appear, including nausea, vomiting, weakness, sweating, and hypotension

In a randomized, placebo-controlled Phase 2a trial, PP405 met its primary safety endpoint and secondary pharmacokinetic endpoint, showed no systemic absorption, and was well tolerated across a diverse patient population
