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Its very unusual to see the extended shortage of a multi-billion dollar drug, leading to the funky dynamics were seeing DTC telehealth players (and in-person med spas, other wellness facilities) want to maximize their economics by expanding access to acquire/grow subscriber bases

Studies show that single-molecule dual GIPR/GLP-1R agonists have better insulinotropic and antihyperglycemic effects than GLP-1 agonists in rodents, primates, and humans, without causing gastrointestinal disturbances [58]

Jiangsu Hengrui Chinas largest domestic pharma had Novos patent overturned at the Supreme Peoples Court, though Novo is appealing
The cardiovascular effects of retatrutide are an area of active investigation

Heat-damaged semaglutide pens may still appear normal and inject normally, but the active compound inside has been compromised

Centre Spring MD founder and podcast host Dr
