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Insulin resistance, obesity, hypertension, and renal sodium transport

A longitudinal study further demonstrated that type 2 diabetes in older community-dwelling individuals is associated with a decline in verbal memory and fluency over approximately 5 years ( The effects of diabetes on brain atrophy may begin as early as midlife

To this end he began exploring leptin, a new hormone discovered in 1994 by Jeffrey Friedman, a molecular geneticist with an interest in weight regulation at Rockefeller University in New York

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