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Sometimes I make a bowl of oatmeal midday, and I struggle to eat it

Orforglipron is the worlds second oral GLP-1 pill for weight management, approved by the FDA in April 2026

Healthy rats treated with retatrutide showed increased BDNF and CREB mRNA expression levels

One side effect that gets people asking questions: dysesthesia TRIUMPH4 reporting mentions dysesthesia (odd, uncomfortable sensations like tingling/burning) and says it was generally mild and infrequently led to discontinuation

Only one study, which evaluated 21 PWS children, reported a case of mild positivity for anti-thyroid peroxidase antibodies ( Regarding hyperthyroidism, a single case with an unclear origin treated with thiamazole was reported in a group of adult patients with PWS ( Based on the data available in the literature, there does not appear to be a clear correlation between genotype and thyroid dysfunction in individuals with PWS

Step 2: If labs make sense, we'll run them