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Why the EUs Lack of Patent Linkage Creates Different Generic Entry Dynamics The EMA has no Orange Book, no Paragraph IV mechanism, and no automatic 30-month stay

Patients with a history of GORD, hiatus hernia, or BMI above 35 are already at elevated reflux risk

N Engl J Med 2009;361:2019-32.PubMed 12

Kids, work, and other commitments can get in the way

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However, important questions remain about their precise mechanisms of action, potential adverse effects, and which patient subgroups are most likely to benefit
