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10.1016/S2213-8587(23)00356-X [DOI] [PubMed] [Google Scholar] 31

Common research applications include single-receptor pharmacology (semaglutide and liraglutide as GLP-1 reference agonists), dual-receptor comparison studies (tirzepatide for GIP/GLP-1, mazdutide and survodutide for GLP-1/glucagon), triple-receptor research (retatrutide), and multi-pathway combinations using amylin agonists alongside incretin agonists (cagri-sema, retatrutide+cagrilintide)

Certain diseases such as chronic bronchitis, COPD, asthma, or emphysema will impair breathing

Rapid weight loss can mean losing water, fat, and muscle
