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In the Phase 2 trial, the cohorts that escalated to higher maintenance doses began at 2mg weekly and increased by 2mg every 4 weeks

As of March 29, 2026 , retatrutide remains investigational , not FDA approved

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A larger clinical trial of the procedure involving more than 300 people is now underway, with early data expected later this year, researchers said

Food and Drug Administration (FDA)-approved to help people manage diabetes and, in some cases, obesity and sleep apnea

He lost 10 lbs, then gained 20
