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Pennock ND, Martinson HA, Guo Q, Betts CB, Jindal S, Tsujikawa T, et al

formerly nonalcoholic fatty liver disease) affects about 25% of adults globally.68 In people living with obesity, the prevalence of MASLD is about 75%, with MASH (formerly nonalcoholic steatohepatitis) affecting about 34%.69 Metabolic dysfunctionassociated steatotic liver disease is strongly associated with cardiometabolic risk factors.70 Its management is focused on weight loss in people with obesity;71 optimization of cardiometabolic risk factors

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Although the levels did not reach the hyperglycemic index for diabetes within the short diet period used, SAD2 did increase blood glucose without glucose or sucrose supplementation

All three medications are once-weekly injections, but their effectiveness, dosing, and cost can differ

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