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Alcohol also contains empty calories and can contribute to dehydration
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Anxiety and stress may also increase mucus in the stool when they coexist with IBS-D
The Nod-like receptor protein 3 (NLRP3) inflammasome is activated by various metabolic stress signals including proinflammatory lipids like ceramides, excessive Ca 2+ efflux from the ER, and mitochondrial damage and oxidative stress
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