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The potential causes of this heterogeneity mainly include population characteristics, drug specificity, the intensity of lifestyle intervention, and the impact of comorbidities [50]

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As body weight decreases, metabolism naturally adapts and calorie needs become lower

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It found that glucagon-like peptide-1 receptor agonists (GLP-1 drugs) like Ozempic may be linked to lower depression risk compared to other diabetes drugs, particularly dipeptidyl peptidase-4 inhibitors ( DPP4i ) like Januvia

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