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The FDAs decision was supported by data from the Phase II ROSEWOOD trial, in which the BrukinsaGazyva combo led to a 69% overall response rate (ORR) compared to 46% ORR in patients treated with Gazyva alone, according to BeiGene

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Weight loss drugs are approved for use in adults with a BMI of 30 or greater, or a BMI of 27 or higher with weight-related health problems like high blood pressure or type 2 diabetes

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The initial Context of Use was narrow: improve glycaemic control in type 2 diabetes through incretin-mediated pancreatic beta-cell stimulation

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Tirzepatide (Mounjaro, Zepbound): a dual GIP/GLP-1 receptor agonist

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