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[DOI] [PubMed] [Google Scholar] 47.Sanyal AJ, Kaplan LM, Frias JP, Brouwers B, Wu Q, Thomas MK, et al
The scale of effect is fundamentally different - prescription GLP-1 medications have demonstrated 10-20% body weight reductions in clinical trials
The LEADER trial 28 (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) studied a 1.8-mg dose in more than 9,000 patients with type 2 diabetes and found the incidence of acute pancreatitis was similar between the liraglutide and placebo groups (0.4% vs 0.5%, respectively)
Some of the newer drugs like semaglutide, which is known as Ozempic and Wegovy, and tirzepatide, which is known as Mounjaro and Zepbound these drugs have increased potency
2016;22(7 Suppl):s176s185
Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice
