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To put Lillys 25.5% in perspective, previous pivotal trials for Tirzepatide, such as SURMOUNT-1 and SURMOUNT-5, showed weight loss of 20.9% and 20.2% respectively over 72 weeks

Tirzepatide vs Semaglutide At a Glance This table offers a clear snapshot of the key differences between these two leading medications

Maintenance / taper: after a defined cycle, the research pattern is to pause

You may also have weight gain and feel more sensitive to cold

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So far, they have also been studied for their anti-inflammatory and cardioprotective properties in subjects with T2DM who are at high risk for cardiovascular diseases [26], [27]