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These researchers did not account for decrease in other medications and office visits, so the cost effectiveness might be somewhat higher than the authors have expressed

"Retatrutide, a GIP, GLP-1 and glucagon receptor agonist, for people with type 2 diabetes: a randomised, double-blind, placebo and active-controlled, parallel-group, phase 2 trial conducted in the USA." The Lancet 402.10401 (2023): 529-544

+5.9 7.2 nmol/L with TRT), with comparable improvements in sexual function, including libido and erectile performance
pmid:26187122

Tirzepatide often produces greater average weight loss in studies, but the best choice depends on individual needs and tolerance

Patients are encouraged to report any suspected side effects to the MHRA Yellow Card Scheme (yellowcard.mhra.gov.uk)
