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Enteroendocrine cells (EECs), specialized neuroendocrine cells of the intestinal epithelium, mediate this postprandial gut feedback, as they sense the luminal milieu and release gut peptides that influence metabolic homeostasis, such as GLP-1 and cholecystokinin (CCK) 16

Factors such as age, weight, metabolic health, medication history, and side effect tolerance all influence how quickly you should titrate

Mechanisms of Cardiorenal Effects of Sodium-Glucose Cotransporter 2 Inhibitors
is supported by China Thousand Talents Plan (Young Talents), Shaanxi province Thousand Talents Plan (Young Talents), and the Foundation of Xian Jiaotong University (Plan A)

Esser, N., Legrand-Poels, S., Piette, J., Scheen, A

doi: 10.1016/j.phrs.2015.10.008 22 MahapatraMKKaruppasamyMSahooBM
