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11 This adverse effect may be related to GLP-1 R activation in the CNS, which can influence cerebrovascular tone and regional blood flow, potentially resulting in cerebral vasodilatation and headaches due to mechanical strain on pain-sensitive structures

In this article, we describe the potential efficacy of GLP-1RAs for the induction of axonal regeneration and remyelination following nerve lesions and the prevention and alleviation of demyelinating disorders, particularly multiple sclerosis

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Key Facts A record high 11% of Americans are taking a GLP-1 medication for weight loss, according to Gallup , up 3% from 2024
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Smits MM, Fluitman KS, Herrema H et al
