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for research use only Tesamorelin is a synthetic analogue of growth hormone-releasing hormone (GHRH) studied for its potential role in somatotropic signaling, visceral adipose tissue metabolism, and GH/IGF-1 axis modulation

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Of note, combination therapy faces significant barriers, including safety concerns in older or frail individuals, underutilisation in disadvantaged populations, while economic challenges may further hinder the accessibility of these therapies