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The medication then gradually decreases over the following days, which is why weekly dosing keeps levels stable enough to control hunger and blood sugar
The theoretical concern is additive effects on insulin sensitivitybeneficial in some contexts, but potentially requiring dose adjustment or monitoring in others
J Clin Endocrinol Metab 2017
In Phase 2 trials, treatment with survodutide led to greater reductions in both HbA1c levels and body weight compared to placebo after 16 weeks
